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| Sequence Length (bp) | Genome Element |
| 25–75 | SNPs, short frameshift mutations |
| 100–400 | Short functional signatures |
| 500–1,000 | Whole domains, single domain genes |
| 1,000–5,000 | Short operons, multidomain genes |
| 5,000–10,000 | Longer operons, some cis-control elements |
| >100,000 | Prophages, pathogenicity islands, various mobile insertion elements |
| >1,000,000 | Whole prokaryotic chromosome organization |
