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. 2010 Feb 26;6(2):e1000783. doi: 10.1371/journal.ppat.1000783

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Periplasmic and inner membrane uptake proteins for proline (PutP), histidine (HisJMPQ), glutamine (GlnHPQ), arginine (ArtIMPQ), spermidine (PotABCD), and hydroxyphenylacetate (HpaX) are indicated from left to right. Genes encoding catabolic enzymes leading to glutamate and TCA cycle intermediates are also shown. Symbols labeled in blue indicate genes upregulated ≥2-fold in the flea compared to all in vitro conditions (Table S1).