Table 1. Kinetics of Cyr61 interactions with VTNC and SMTB ^1–44.

	ka1 (M−1s−1)	kd1 (s−1)	ka2 (s−1)	kd2 (s−1)	KD (nM)
Monomeric VTNC	5.678×105	0.02454	0.007829	0.001180	5.66
Multimeric VTNC	1.043×105	0.06954	0.002555	0.000110	27.55
SMTB 1–44	1.273×105	0.02501	0.01094	0.000592	10.09

Responses were obtained by injecting Cyr61 over immobilized VTNC or SMTB ^1–44 for 90 seconds at a flow rate of 30 µl/minute. Data fitting using two-site binding model (conformational change). Kinetic values obtained from the sensorgrams are presented in Figure 2, C and D, and in Figure 3E.