Table 3. Relationship between co-morbidity parameters on maximal oral feeding (N=175).
| Morbidity/intervention variable | Unadjusted OR (CI) | P value | Adjusteda OR (CI) | P value |
|---|---|---|---|---|
| Gestational age, weeks | 1.25 (1.11, 1.40) | 0.0002 | 1.20 (1.00, 1.44) | 0.05 |
| Hypotension | 0.33 (0.16, 0.67) | 0.003 | 0.97 (0.36, 2.59) | 0.95 |
| Caffeine | 0.70 (0.36, 1.40) | 0.32 | 3.04 (1.04, 8.91) | 0.04 |
| PDA | 0.30 (0.09, 1.00) | 0.05 | 1.11 (0.27, 4.59) | 0.89 |
| GER | 0.43 (0.19, 0.96) | 0.04 | 0.59 (0.24, 1.48) | 0.26 |
| Ventilation | 0.16 (0.06, 0.42) | 0.0002 | 0.27 (0.08, 0.88) | 0.03 |
| NCPAP | 0.35 (0.17, 0.74) | 0.006 | 0.77 (0.28, 2.13) | 0.62 |
| Positive blood culture | 0.22 (0.10, 0.46) | 0.0001 | 0.36 (0.14, 0.89) | 0.03 |
Abbrevations: GER, gastroesophageal reflux; PDA, patent ductus arteriosus.
a
Adjusted for all variables displayed in the table. Interpretation: if a subject's gestational age (GA) is older by 1 week, then this subject will have 1.25 times chance to get to maximal oral feeding based on GA alone; however, if all other co-existing conditions remain same, then the chance to achieve this milestone is 1.2 times. Similarly, if a patient is ventilated, then this patient will only have 0.16 times chance to get to maximal oral feeding compared with those without the need for ventilation, and 0.27 times chance to get to maximal oral feeding if all other co-existing conditions remain same.