Figure 6.

CRE-SPAP production in CHO-A1 cells in response to NECA-dansyl derivatives (AUEA-dansyl, ABEA-AO-dansyl and ABEA-dansyl). Bars show basal CRE-SPAP production, that in response to 3 µM forskolin. Data points are mean ± SEM from triplicate values from a single experiment and this is representative of seven separate experiments. ABEA, N⁶-(4-aminobutyl)-5′-ethylamino-5′-oxo-5′-deoxyadenosine; AUEA, N⁶-(11-aminoundecyl)-5′-ethylamino-5′-oxo-5′-deoxyadenosine; CHO, Chinese hamster ovary; CRE-SPAP, cyclic AMP response element-secreted placental alkaline phosphatase; NECA, 5′ (N-ethylcarboxamido)adenosine.