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QAPB binding (1 µM) in MMA taken from WT, α1BD- and α1ABD-adrenoceptor knockout (KO) mice. Reduced binding was observed in arteries from both KO mice. Histogram analysis of image stacks from six samples from WT, five from BDKO and one from ABD KO shows an overall reduction in total fluorescence/binding in KO arteries throughout the vascular wall.
