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. 2010 Jan 25;159(4):856–871. doi: 10.1111/j.1476-5381.2009.00581.x

Figure 1.

Figure 1

Effect of deoxyelephantopin (DET) on cell proliferation, colony formation, wound healing, migration and invasion of TS/A cells. (A) Chemical structure of DET. (B1) CCD966SK, M10, MDA-MB-231, MCF-7 and TS/A cells were treated with vehicle (0.1% dimethyl sulphoxide) or the indicated concentrations of DET at 37°C for 48 h, and cell viability (%) was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. (B2) Colony formation of TS/A cells was determined in a clonogenic assay. (C) Wound healing of TS/A cells treated with or without DET or paclitaxel at 37°C for 48 h; wound recovery was measured as a percentage of original wound size. (D1) and (D2) Migration and invasion analyses of TS/A cells. Data are mean ± SEM of six independent experiments. Different letters indicate significant differences (one-way anova). *P < 0.05.