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. Author manuscript; available in PMC: 2010 Feb 26.
Published in final edited form as: Science. 2010 Jan 14;327(5967):863–866. doi: 10.1126/science.1181886

Figure 1. Altered extinction in mice and humans with BDNF Val66Met.

Figure 1

Impaired extinction in Met allele carriers (Val/Met and Met/Met) as a function of time in 68 mice (A) and 72 humans (B) as indexed by percent time freezing in mice and skin conductance response (SCR) in humans to the conditioned stimulus when it was no longer paired with the aversive stimulus. All results are presented as a mean ± SEM. *p < 0.01, Student’s t test. **p < 0.02, Student’s t test. VV = Val/Val; VM = Val/Met; MM= Met/Met.