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. Author manuscript; available in PMC: 2010 Feb 26.
Published in final edited form as: Development. 2008 Jan 16;135(4):717–727. doi: 10.1242/dev.015339

Table 1. Reciprocal embryo transfer in mice receiving either DKK1 ADV or empty vectors.

Treatment
No. of blastocysts
transferred
No. of
recipients
No. of mice
with IS (%)
No. of IS
(%)
No. of blastocysts recovered
from mice without IS (%)
Embryo donors Recipients
No treatment Empty ADV 104 7 7 (100%) 60 (58%) N/A
No treatment DKK1 ADV 135 9 9 (100%) 73 (54%) N/A

Empty ADV No treatment 82 6 6 (100%) 46 (56%) N/A
DKK1 ADV No treatment 98 8 1 (13%)* 5 (5%)* 28 (29%)

Normal day 4 blastocysts retrieved from untreated mice were transferred into day 4 pseudopregnant recipients receiving treatments of either DKK1 ADV or empty vectors. Conversely, blastocysts retrieved from pregnant females receiving either DKK1 ADV or empty vectors were transferred into the uterine horn of normal untreated pseudopregnant recipients on day 4 midmorning. Implantation was examined 24 hours later by blue dye method. N/A, not applicable.

*

P<0.05 (Student t-test).

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