Abstract
A correlation of the crystal structure analyses of the potent nicotinic agonists acetylcholine, acetyl-α-methylcholine, lactoylcholine, 1,1-dimethyl-4-phenylpiperazine, and nicotine allows one to determine the conformation of cholinergic agonists relevant to nicotinic nerve receptors.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Canepa F. G., Pauling P., Sörum H. Structure of acetylcholine and other substrates of cholinergic systems. Nature. 1966 May 28;210(5039):907–909. doi: 10.1038/210907a0. [DOI] [PubMed] [Google Scholar]
- Chiou C. Y., Long J. P., Cannon J. G., Armstrong P. D. The cholinergic effects and rates of hydrolysis of conformationally rigid analogs of acetylcholine. J Pharmacol Exp Ther. 1969 Apr;166(2):243–248. [PubMed] [Google Scholar]
- Chothia C., Pauling P. Conformation of cholinergic molecules relevant to acetylcholinesterase. Nature. 1969 Aug 30;223(5209):919–921. doi: 10.1038/223919a0. [DOI] [PubMed] [Google Scholar]
- Chothia C., Pauling P. Conformations of acetylcholine. Nature. 1968 Sep 14;219(5159):1156–1157. doi: 10.1038/2191156a0. [DOI] [PubMed] [Google Scholar]
- Liquori A. M., Damiani A., De Coen J. L. Calculated minimum energy conformations of acetylcholine. J Mol Biol. 1968 Apr 28;33(2):445–450. doi: 10.1016/0022-2836(68)90201-5. [DOI] [PubMed] [Google Scholar]
- WILLEY G. L. Stimulant activities of quaternary ammonium compounds on mammalian skeletal muscle. Br J Pharmacol Chemother. 1955 Dec;10(4):466–473. doi: 10.1111/j.1476-5381.1955.tb00107.x. [DOI] [PMC free article] [PubMed] [Google Scholar]