. Author manuscript; available in PMC: 2010 Feb 26.

Published in final edited form as: Radiat Res. 2008 Jul;170(1):70–82. doi: 10.1667/RR1072.1

TABLE 1.

Comparison of DSB Yields among Different Forms of Plasmid DNA: Dependence on DNA Topology

	D_0DSB × 10¹³ (decays/ml)			DSBs/decay
Topological state of plasmid DNA	−DMSO	+DMSO	DMF_D0DSB	−DMSO	+DMSO
				0.54 ± 0.02^*	0.50 ± 0.03^*
Supercoiled	5.65 ± 0.19	6.12 ± 0.34	1.08 ± 0.07	0.52 ± 0.02^*
Linear	1.89 ± 0.08	4.02 ± 0.16	2.13 ± 0.12	1.62 ± 0.07	0.76 ± 0.03
Nicked circular	1.76 ± 0.11	2.93 ± 0.20	1.66 ± 0.16	1.74 ± 0.11	1.05 ± 0.07

P = 0.2.