Table 4.
Comparison of tumor characteristics by treatment group
| Any Treatment (n=1256) |
No Treatment (n=1068) |
p-value | ||
|---|---|---|---|---|
| EGFR | EGFR+ | 22% | 14% | p < 0.0001 |
| EGFR− | 78 | 86% | ||
| Age (years) | Median Age | 57 | 65 | |
| < 50 years | 34% | 18% | p < 0.0001 | |
| ≥ 50 years | 66% | 82% | ||
| Tumor Size (cm) | > 2 cm | 55% | 41% | |
| ≤ 2 cm | 45% | 59% | p < 0.0001 | |
| Positive Nodes | > 3 | 22% | 6% | |
| 1–3 | 30% | 14% | p < 0.0001 | |
| 0 | 48% | 80% | ||
| Tumor Ploidy | Aneuploid | 53% | 45% | |
| Diploid | 47% | 55% | p = 0.0002 | |
| S-phase | High | 31% | 22% | |
| Intermediate | 21% | 19% | p < 0.0001 | |
| Low | 47% | 58% | ||
| ER | Negative | 18% | 14% | |
| Positive | 82% | 86% | p = 0.0118 | |
| PR | Negative | 42% | 41% | |
| Positive | 58% | 59% | p = 0.6068 | |
| HER2 | Positive | 19% | 16% | |
| Negative | 81% | 84% | p = 0.0560 |