Table 2.
Antiproliferative Activity of 1.
| Cancer cell line | IC50 (μg/mL) |
|---|---|
| H522-T1 (non-small cell lung) | 1.2 |
| MDA-MB-435 (melanoma) | 3.0 |
| U937 (lymphoma) | 1.5 |
| BT-549 (breast) | 45 |
| DU 145 (prostate) | 34 |
| H460 (large cell lung) | 17–50 |
| HCC-2998 (colon) | > 50 |
| HT-29 (colon) | > 50 |
| MCF-7 (breast) | > 50 |
| OVCAR-5 (ovarian) | > 50 |
| SF-539 (gliosarcoma) | > 50 |
| SR (lymphoma) | > 50 |
| UACC-257 (melanoma) | > 50 |