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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Int Immunopharmacol. 2009 Dec 18;10(3):308–315. doi: 10.1016/j.intimp.2009.12.001

Figure 3. Nicotinic effects on IL-10 production by LPS-stimulated U937 cells.

Figure 3

A, B. Differentiated U937 cells were stimulated with LPS in the presence or absence of 1 μM Epi ± 50 μM Mec or 100 nM MLA, or 100 μM AR-R17779 (AR) ± 100 nM MLA and used in the qPCR (A) and ICW (B) assays of the IL-10 gene expression as described in the legend to Fig. 2. Asterisk = p<0.05 compared to LPS given alone; pound sign = p<0.05 compared to the relevant agonist given alone.

C. Concentration-dependent effects of Epi and AR-R17779 on the level of IL-10 protein in differentiated U937 cells stimulated with LPS.

The results are expressed as fold of control determined in control PMA-differentiated U937 cells, and taken as 1.