Table 2.

Morphologic Findings with and without α-Chymotrypsin Treatment to Lyse the Vitreous Zonule in Monkey Eyes

A. Apical Position and Muscle Width
Monkey	Age (y)		Apical Position (mm)				Muscle Width (mm)
			Temporal	Inferior	Superior	Nasal	Temporal	Inferior	Superior	Nasal
1	3.50	Postlysis	0.51	0.49	0.53	0.61	0.67	0.54	0.60	0.76
		Control	0.55	0.51	0.53	0.64	0.60	0.53	0.53	0.62
2	6–8	Postlysis	0.32	0.55	0.57	0.76	0.60	0.60	0.70	0.59
		Control	0.59	0.72	0.55	0.47	0.68	0.51	0.59	0.60
3	9.00	Postlysis	0.31	0.27	0.45	0.64	1.01	0.98	1.04	1.04
		Control	0.53	0.64	0.63	0.39	0.86	0.80	0.85	0.80
4	9.50	Postlysis	0.23	0.31	0.37		0.94	0.91	0.88	0.88
		Control	0.76	0.85	0.85	0.55	0.67	0.72	0.73	0.79
5†	25.00	Postlysis	0.42	0.45	0.53	0.59	0.71	0.72	0.67	0.72
		Control	0.64	0.56	0.58	0.47	0.63	0.73	0.71	0.64

B. Differences in Apical Position and Muscle Width
Monkey	Apical Position (mm) α-Chymotrypsin–Treated minus Control Eye				Muscle Width (mm) α-Chymotrypsin–Treated minus Control Eye
	Temporal	Inferior	Superior	Nasal	Temporal	Inferior	Superior	Nasal
1	−0.04	−0.02	0.0	−0.03	0.07	0.01	0.07	0.14
2*	−0.27	−0.17	0.02	0.29	−0.08	0.09	0.11	−0.01
3*	−0.22	−0.37	−0.18	0.25	0.15	0.18	0.19	0.24
4*	−0.53	−0.54	−0.48		0.27	0.19	0.15	0.09
5†	−0.22	−0.11	−0.05	0.12	0.08	−0.01	−0.04	0.08
Mean	−0.256*	−0.242	−0.138	0.158	0.098	0.092	0.096	0.108
SEM	0.079	0.094	0.092	0.072	0.057	0.042	0.039	0.041
P	0.044	0.062	0.209	NS	0.161	0.091	0.072	0.058

Data show the apical position and muscle width (A) and the differences in muscle apical position and muscle width (B) between α-chymotrypsin-treated and control monkey eyes in the respective quadrants. The eyes received α-chymotrypsin injection in the temporal quadrant to lyse the vitreous zonule (Postlysis). The apical position of the muscle was farther anterior in the α-chymotrypsin–injected eyes than in the contralateral control eyes. The difference was most pronounced near the injection site (temporal quadrant; P = 0.044, by two-tailed paired t-test). Overall the muscle width tended to be thicker in the α-chymotrypsin–injected eyes than in the contralateral control eyes, but the change in width was not dependent on proximity to the injection site. NS, not significant. Monkey 1 was cynomolgus and monkeys 2–5 were rhesus.

^*Pseudophakic eyes.

^†Aphakic eye.