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. Author manuscript; available in PMC: 2011 Mar 15.
Published in final edited form as: Biol Psychiatry. 2009 Oct 14;67(6):584–587. doi: 10.1016/j.biopsych.2009.08.024

Figure 1. Altered Functional Connectivity to the Precuneus.

Figure 1

All images are shown in medial sagittal section and identify statistically significant regional differences in functional connectivity of the precuneus between AD and (PIB−) cognitively normal individuals (blue) and between (PIB+) and (PIB−) cognitively normal individuals (red). The top left (1a) and right (1c) images display the left medial surfaces in AD vs PIB− and PIB+ vs PIB− participants, respectively. The second row left (1b) and right (1d) images display the right medial sagittal surfaces in the AD vs PIB− and PIB+ vs PIB− participants, respectively. The regions identified were in visual cortex-(VC) (both L and R), L hippocampus—(L hip), L parahippocampus—(L parahip), L anterior cingulate (AC), L (AD only) and R gyrus rectus (GR)(both groups). For brevity, not shown are the dorsal cingulate (DC) and superior precuneus (sup PC) regions. The graph compares regional correlation magnitudes for AD, PIB+ and PIB− individuals. *p-values denote significant differences in connectivity between (PIB+) and (PIB−) groups.