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. Author manuscript; available in PMC: 2010 Feb 27.
Published in final edited form as: Reprod Toxicol. 2008 Nov 1;27(3-4):299–306. doi: 10.1016/j.reprotox.2008.10.003

Table 2.

Effects of PFOA treatment on mammary gland ductal length, the number of terminal end buds (TEBs) and the number of stimulated terminal ducts (TDs) (Mean ± SD, n=5)

Treatment Ductal Length (relative units) Number of TEBs Number of stimulated TDs
Balb/c
Vehicle 7.60 ± 0.94c,d 8.20 ± 1.92c,d 6.20 ± 2.39c,d
1 mg/kg 7.28 ± 0.73c,d 6.00 ± 3.74d 3.80 ± 1.64d
5 mg/kg 3.99 ± 0.36a,b 3.99 ± 0.36a,d 1.20 ± 1.30a,d
10 mg/kg 3.40 ± 4.77a,b 0.00 ± 0.00a,b,c .00 ± 0.00a,b,c
C57BL/6
Vehicle 4.76 ± 1.19d 7.80 ± 2.39c,d 6.60 ± 2.88c,d
1 mg/kg 4.06 ± 0.85d 10.40 ± 3.36d 9.80 ± 2.77c,d
5 mg/kg 4.01 ± 0.71d 11.20 ± 1.30a,d 16.60 ± 5.90a,b,d
10 mg/kg 0.30 ± 0.67a,b,c 0.00 ± 0.00a,b,c 0.00 ± 0.00a,b,c
a

p<0.05, compared to Vehicle control group;

b

p<0.05, compared to 1 mg/kg PFOA treatment group;

c

p<0.05, compared to 5 mg/kg PFOA treatment group;

d

p<0.05, compared to 10 mg/kg PFOA treatment group.