Skip to main content
. Author manuscript; available in PMC: 2010 Feb 27.
Published in final edited form as: IEEE Rev Biomed Eng. 2008 Dec 16;1(1):75–93. doi: 10.1109/RBME.2008.2008241

Fig. 5.

Fig. 5

Example of sorting protocol to obtain progenitor cells or mammary repopulating units (MRU’s) from the mammary gland of a mouse. CD24 and CD49f are used, along with various lineage markers are used in FAC sorting to obtain the above plot. Only cells in the MRU identified region are suggested as being highly enriched for cells that can reconstitute an entire gland from a single cell. Additionally, Ma-CFCs = mammary colony-forming cells and MRUs = mammary repopulating units [32]. (Figure reprinted with permission from Macmillan Publishers, Nature, 2006.)