FIG. 5.

A mesothelioma tissue array, which consists of 48 primary tumor biopsies, was stained with antibodies against IFNAR1 (A), p48 (B), and PKR (C) and an immunoreactive staining score (see Materials and Methods section) was determined for each tumor. (A–C) The distribution of the immunoreactive score for each antibody. An immunoreactive score of 2 or less indicates an absence or low expression of that particular protein. (D) The number of defects per tumor is plotted. Forty-five percent of tumors had no defects, approximately 30% of tumors had lost staining in one protein, and 25% had lost staining in two or three of the proteins.