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Transduction of neuronal cells of spinal cord via retrograde transport of AAV-CMV-LacZ vector. Costaining of anti-beta-galactosidase (LacZ) and anti-neuronal nuclei (NeuN) of lumbar spinal cord showed some colocalization of NeuN-positive cells with LacZ (white arrows)-positive signal, demonstrating that neurons in the spinal cord were transduced. The inset is a magnification of an LacZ-positive neuron. Color images available online at www.liebertonline.com/hum.
