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. 2009 Dec 17;21(1):87–97. doi: 10.1089/hum.2009.131

FIG. 7.

FIG. 7.

Characterization of LacZ-positive cells in peripheral nerves in mice injected intramuscularly. (A) Neuron axon was transduced by AAV-CMV-LacZ vector. Colocalization of LacZ and neurofilament (nerve fiber marker) indicated that neuronal axons in peripheral nerves were transduced by AAV-CMV-LacZ vector (white arrowheads). The inset is an enlarged magnification of an LacZ-positive neuronal axon (cross section). (B) Schwann cells were also transduced by AAV-CMV-LacZ vector via retrograde. Colocalization of LacZ and the myelin basic protein (MBP) indicated that myelinating Schwann cells were also transduced (white arrows).