Table 3.

DNMT3A -448A>G genotype and allele frequencies in control subjects

Groups	Genotype			Allele
	GG (%)	AG (%)	AA (%)	A (%)	P *
Total	218 (63.0)	118 (34.1)	10 (2.9)	19.9
Age years)					0.09†
≤60	80 (23.1)	57 (16.5)	4 (1.2)	9.4
>60	138 (39.9)	61 (17.6)	6 (1.7)	10.5
Gender					0.521‡
Male	152 (43.9)	82 (23.7)	9 (2.6)	14.5
Female	66 (19.1)	36 (10.4)	1 (0.3)	5.5

*Chi-squared test.

† The frequency of A allele in individuals at ≤ 60 years versus > 60 years.

‡ The frequency of A allele in individuals in male versus female.