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. 2010 Feb 12;7:5. doi: 10.1186/1743-8454-7-5

Table 2.

The CSFP pulse during lumbar puncture versus ICP pulse during over-night ICP monitoring

Over-night ICP monitoring* Lumbar puncture



ICP wave amplitude CSFP wave amplitude during opening phase CSF wave amplitude during lumbar infusion


< 2 mmHg ≥ 2 mmHg < 4 mmHg ≥ 4 mmHg
< 4 mmHg (n = 20) 17 3 12 8
≥ 4 mmHg (n = 42) 17 25 5 37


Statistics Sensitivity = 60; Specificity = 85
PPV = 89; NPV = 50
Sensitivity = 88; Specificity = 60
PPV = 82; NPV = 71

*Mean ICP wave amplitude from the period 11 p.m. to 7 a.m.