Table 6.
Significant polymorphic sites identified in Exp. 2 in comparison to Exp. 1
| Gene | Exp.2 polymorphisms | Exp.1 | |||
|---|---|---|---|---|---|
| Site | Region | SNP/Indel | aa Change | p-value | |
| 342 | Prom | A-T | - | - | |
| COMT | 659* | Prom | 1 | - | - |
| 749* | E1 | 6 | - | 0.99 | |
| 1948* | I1 | G-T | - | 0.03 | |
| 1981* | I1 | C-T | - | 0.92 | |
| CCoAOMT1 | 704* | I3 | 3 | - | - |
| 734* | I3 | 2 | - | 1 | |
| 944* | I4 | C-G | - | 0.01 | |
| 956* | I4 | 11 | - | - | |
| 972* | I4 | A-G | - | - | |
| CCoAOMT2 | 187* | E1 | A-G | His - Arg | - |
| 688* | I3 | A-G | - | - | |
| 717* | I3 | C-T | - | - | |
| 720* | I3 | C-T | - | - | |
E: exon; I: intron; Prom: promoter; aa: Amino Acid; Syn.: Synonymous substitution; *: singleton
Site numbers denote bp alignment position of individual SNPs and starting position of Indels based on the reference sequences AY323283, AY323264 and AY279022, for COMT, CCoAOMT1 and CCoAOMT2, respectively.