Table 3.
Responsiveness, Power, and Sample Size Requirementsa
| Responsiveness Index (or Effect Size) | SD | Sample Size, No. | Power |
|---|---|---|---|
| CLASI Activity Change of 11.0 | |||
| 0.20 | 55.0 | 60 | 0.80 |
| 0.40 | 27.5 | 40 | 0.84 |
| 50 | 0.87 | ||
| 55 | 0.90 | ||
| 0.50 | 22.0 | 25 | 0.78 |
| 30 | 0.85 | ||
| 35 | 0.89 | ||
| 40 | 0.93 | ||
| 0.61 | 18.0 | 15 | 0.73 |
| 20 | 0.84 | ||
| 25 | 0.91 | ||
| 0.80 | 13.8 | 10 | 0.75 |
| 15 | 0.90 | ||
| 1.00 | 11.0 | 10 | 0.90 |
|
| |||
| CLASI Activity Change of 9.0 | |||
| 0.20 | 45.0 | 60 | 0.45 |
| 0.40 | 22.5 | 40 | 0.80 |
| 45 | 0.84 | ||
| 50 | 0.87 | ||
| 55 | 0.90 | ||
| 0.50 | 18.0 | 25 | 0.78 |
| 30 | 0.85 | ||
| 35 | 0.89 | ||
| 40 | 0.93 | ||
| 0.60 | 15.0 | 20 | 0.83 |
| 25 | 0.90 | ||
| 30 | 0.94 | ||
| 0.80 | 11.3 | 10 | 0.75 |
| 15 | 0.90 | ||
| 1.00 | 9.0 | 10 | 0.90 |
Abbreviation: CLASI, Cutaneous Lupus Erythematosus Disease Area and Severity Index.
One sample, paired t test; α=.05; 1-tailed; SD unknown. Power calculations were performed using PASS statistical software (Number Cruncher Statistical Systems, Kaysville, Utah).