TABLE 2.
Total |
COMB |
FLX |
CBT |
PBO |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Domain | Assessment | N | M ± SD | N | M ± SD | N | M ± SD | N | M ± SD | N | M ± SD |
Depression | CDRS–R total score | ||||||||||
Baseline | 439 | 60.1 ± 10.4 | 107 | 60.8 ± 11.6 | 109 | 59.0 ± 10.2 | 111 | 59.6 ± 9.2 | 112 | 61.1 ± 10.5 | |
Week 6 | 389 | 42.1 ± 12.3 | 98 | 38.5 ± 12.7 | 99 | 39.4 ± 11.5 | 97 | 45.3 ± 11.8 | 95 | 45.4 ± 11.6 | |
Week 12 | 378 | 38.2 ± 13.4 | 95 | 33.4 ± 11.9 | 97 | 36.8 ± 12.7 | 90 | 41.4 ± 14.2 | 96 | 41.4 ± 13.4 | |
Suicidality | SIQ-Jr total score | ||||||||||
Baseline | 439 | 23.5 ± 21.6 | 107 | 27.2 ± 24.5 | 109 | 21.8 ± 19.1 | 111 | 21.8 ± 21.0 | 112 | 23.4 ± 21.3 | |
Week 6 | 362 | 15.2 ± 17.6 | 86 | 14.2 ± 18.4 | 95 | 16.1 ± 18.5 | 89 | 12.8 ± 14.9 | 92 | 17.6 ± 18.3 | |
Week 12 | 370 | 13.4 ± 16.5 | 90 | 12.5 ± 16.5 | 97 | 14.8 ± 17.3 | 91 | 11.9 ± 14.9 | 92 | 14.4 ± 17.3 | |
Perfectionism | DAS subscale score | ||||||||||
Baseline | 439 | 53.7 ± 17.3 | 107 | 54.1 ± 17.4 | 109 | 52.2 ± 16.3 | 111 | 52.3 ± 17.3 | 112 | 56.0 ± 18.0 | |
Week 6 | 307 | 48.2 ± 17.5 | 71 | 44.2 ± 18.7 | 84 | 46.6 ± 17.3 | 76 | 51.3 ± 16.2 | 76 | 50.5 ± 17.3 | |
Week 12 | 368 | 45.2 ± 19.6 | 89 | 40.0 ± 20.8 | 97 | 46.1 ± 19.4 | 87 | 47.5 ± 16.9 | 95 | 47.1 ± 20.3 | |
Change score-unadjusted | 368 | 9.2 + 17.2 | 89 | 14.8 + 17.5 | 97 | 6.4 + 16.8 | 87 | 5.7 + 14.4 | 95 | 10.1 + 18.6 | |
Change score-adjusted | 439 | 8.8 + 16.2 | 107 | 14.4 + 16.0 | 109 | 6.6 + 15.9 | 111 | 5.5 + 12.8 | 112 | 9.6 + 17.2 |
Note. COMB = CBT and fluoxetine; FLX = fluoxetine; CBT = cognitive behavior therapy; PBO = pill placebo; CDRS–R = Children’s Depression Rating Scale–Revised total score; SIQ-Jr = The Suicidal Ideation Questionnaire Grades 7–9 total score; DAS = Dysfunctional Attitudes Scale Perfectionism subscale score.