TABLE 2.

Independent Research Projects at PROMIS Primary Research Sites

PI, Institution	Independent Project	Patient Population(s)
Harry A. Guess, MD, Darren   DeWalt, MD, University of   North Carolina at Chapel   Hill	Develop PRO item bank measuring important health domains for children;   develop and pilot-test CAT tool for children 8–17 yr	Children (8+ yr), range of   chronic illnesses and   healthy children, large   sample of asthma
James F. Fries, MD, Stanford   University	Develop improved instruments for arthritis and aging outcome assessment;   encourage use of instruments in clinical research	Arthritis, aging
Kevin Weinfurt, PhD, Duke   University	Identify and address challenges related to implementation of PROMIS   technology in multicenter clinical trials	Chronic pain; psychiatric,   cardiovascular disorders;   cancer
Arthur A. Stone, PhD, Stony   Brook University	Assess and improve ecological validity of PROs by comparing real-time   reports of symptoms with retrospective reports as currently assessed with   PROs. Understand how testing contexts (including instructional sets and   comparison standards) for PRO administration affect responses	Rheumatic disease,   community sample
Dagmar Amtmann, PhD,   University of Washington	Develop dynamic system for measuring pain and fatigue; increase scientific   understanding of pain and fatigue in children and adults with disabilities	MS, SCI, neuro-   developmental disorders;   neuromuscular disorders;   TBI; amputation
Paul A. Pilkonis, PhD,   University of Pittsburgh	Development and testing of a core battery for sleep-wake functioning	Psychiatric patients, patients   with sleep disorders,   community sample

PRO indicates patient-reported outcomes; CAT, computerized adaptive testing; MS, multiple sclerosis; SCI, spinal cord injury; TBI, traumatic brain injury.