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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Pediatr Res. 2010 Mar;67(3):244–249. doi: 10.1203/PDR.0b013e3181ca0d93

Figure 3.

Figure 3

The effect of hyperoxia and iNO on numbers of macrophages, mast cells, and eosinophils in neonatal mouse lungs. A) The mean ± SEM of the macrophage numbers from all of the sections stained for CD68. There were substantially greater macrophage numbers in the lung sections from >95% O2 exposed mice than in those from RA controls, and the addition of iNO to the >95% O2 exposure prevented the hyperoxia-induced increase in macrophage numbers. * different from room air, p<0.05. ‡ different from >95% O2, p<0.05. B) The mean ± SEM of the mast cell numbers from all of the lung sections stained with toluidine blue. Hyperoxic exposure significantly decreased mast cell numbers in the lung compared to room air controls, and the addition of iNO to the >95% O2 exposure attenuated the hyperoxia-induced decrease in mast cell numbers in the lung. * different from room air, p<0.05. ‡ different from >95% O2, p<0.05. C) The mean ± SEM of the eosinophil numbers from all of the sections stained with vital new red. There were no significant differences between the 4 groups in eosinophil numbers in the lung.