Table 2.
Two-year average annual breast cancer incidence and mortality rates in non-Hispanic white women
| San Francisco Bay area | The rest of California | |||
|---|---|---|---|---|
| 2000–2001 Rate (95% CI) |
2003–2004 Rate (95% CI) |
2000–2001 Rate (95% CI) |
2003–2004 Rate (95% CI) |
|
| Mortality rate | 27.4 (25.7–29.2) | 26.5 (24.9–28.3) | 27.8 (27.1–28.6) | 25.4 (24.6–26.1) |
| In situ incidence rate | 35.6 (33.6–37.7) | 33.2 (31.3–35.2) | 30.5 (29.7–31.4) | 29.5 (28.7–30.4) |
| Invasive incidence rate | 160.0 (155.9–164.3) | 140.8 (136.9–144.8) | 151.7 (149.9–153.6) | 135.1 (133.4–136.9) |
| Histologic subtypea | ||||
| Ductal | 110.9 (107.5–114.5) | 97.0 (93.7–100.3) | 98.9 (97.4–100.4) | 88.4 (87.0–89.8) |
| With lobular component | 29.6 (27.8–31.5) | 26.9 (25.2–28.7) | 30.4 (29.6–31.2) | 27.0 (26.2–27.8) |
| Age at diagnosis (years)a | ||||
| <40 | 13.1 (11.5–15.0) | 14.0 (12.1–16.1) | 13.0 (12.2–13.9) | 13.0 (12.2–13.9) |
| 40–69 | 305.5 (295.4–315.8) | 263.1 (253.9–272.5) | 287.3 (282.8–291.9) | 255.5 (251.3–259.7) |
| ≥70 | 535.3 (511.7–559.8) | 475.7 (452.4–499.9) | 511.6 (501.3–522.0) | 447.8 (438.0–457.7) |
| ER/PR statusa | ||||
| ER+/PR+ | 96.0 (92.7–99.3) | 83.7 (80.7–86.8) | 76.0 (74.7–77.3) | 65.9 (64.7–67.2) |
| ER+/PR- | 19.5 (18.0–21.0) | 15.3 (14.1–16.7) | 15.9 (15.3–16.5) | 14.1 (13.5–14.6) |
| ER-/PR+ | 2.3 (1.8–2.9) | 1.0 (0.7–1.4) | 1.9 (1.7–2.1) | 1.3 (1.1–1.5) |
| ER-/PR- | 21.6 (20.1–23.3) | 20.3 (18.8–21.9) | 20.5 (19.8–21.3) | 19.6 (18.9–20.2) |
| Missing | 20.7 (19.3–22.3) | 20.3 (18.9–21.9) | 37.4 (36.5–38.4) | 34.3 (33.4–35.1) |
| Stage at diagnosisa | ||||
| Localized | 103.4 (100.1–106.8) | 93.1 (89.9–96.4) | 95.0 (93.5–96.5) | 84.6 (83.3–86.0) |
| Regional | 48.4 (46.1–50.8) | 40.5 (38.4–42.7) | 47.8 (46.8–48.9) | 42.0 (41.0–43.0) |
| Distant | 6.0 (5.2–6.9) | 5.3 (4.5–6.1) | 5.4 (5.0–5.8) | 5.5 (5.2–5.9) |
| Unstaged/Not available | 2.3 (1.8–2.8) | 1.5 (1.1–1.9) | 3.4 (3.2–3.7) | 2.2 (2.0–2.5) |
| Tumor size | ||||
| <2 cm | 93.4 (90.2–96.7) | 82.6 (79.6–85.7) | 84.8 (83.4–86.2) | 73.9 (72.6–75.2) |
| ≥2 cm | 58.1 (55.6–60.7) | 51.6 (49.2–54.1) | 58.2 (57.0–59.4) | 53.5 (52.4–54.6) |
| Unknown | 8.5 (7.6–9.5) | 6.1 (5.3–6.9) | 8.8 (8.3–9.2) | 7.1 (6.7–7.5) |
All rates per 100,000 and age-adjusted to the 2000 US age standard. aInvasive breast cancer. CI, confidence interval; ER, estrogen receptor. Data from the California Cancer Registry.