Table 2.

Summary of the family annotation of assembled peptides versus unassembled reads for the four ocean virus datasets

Sample	Family	Add-on	Example
Arctic Ocean	598	34	PTHR22748
Sargasso Sea	270	5	PTHR11527
Coast of British Columbia	361	9	PTHR10566
Gulf of Mexico	438	25	PTHR17630

The “Family” column lists the total number of protein families that are found from unassembled reads. The “Add-on” column lists the additional PANTHER protein families that are detected by using assembled peptides. The last column gives a few examples of the additional protein families (or functions) that are annotated based the assembled peptides only: PTHR22748, AP endonuclease (E-value = 5.4e-12); PTHR11527 (subfamily SF15), heat shock protein 16 (E-value = 1.5e-07); PTHR10566 (subfamily SF7), ubiquinone biosynthesis protein AARF (E.coli)/ABC (Yeast)-related (E-value = 7.3e-11); PTHR17630 (subfamily SF20), carboxymethylenebutenolidase (Evalue = 4.7e-08) .