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Relationship between normalized mean cord cross-sectional area (CSAn) and disease duration, for a) the Losseff method at C2 and b) the new AS method between C2 and C5. Relapsing-remitting (RR; n=18) and secondary-progressive (SP; n=20) MS patients are shown separately, but for the pooled data, statistically-significant relationships are seen for neither the Losseff method (r = −0.17; p =0.32) nor the AS method (r = −0.30; p = 0.074), after adjusting for age and sex.
