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. 2010 Mar;196(3):186–191. doi: 10.1192/bjp.bp.109.063677

Table 5.

Age at which the adverse childhood experience (ACE) begins to have an effect in predicting DSM–IV disorder onseta

4-12 years age group OR (95% CI) 13-24 years age group OR (95% CI) 25+ years age group OR (95% CI)
Parent death
1.6 (0.3-8.7)
1.8 (0.3-11.4)
4.9 (1.0-24.1)*
Other parent loss
1.4 (0.2-8.2)
0.70 (0.1-5.4)
0.6 (0.1-2.2)
Parent mental health or substance use disorder
4.0 (0.7-23.4)
3.8 (0.6-26.5)
13.9 (2.0-96.0)*
Family violence/criminal behaviour
0.1 (0.0-0.5)
0.6 (0.1-3.7)
0.2 (0.0-1.8)
Neglect/abuse
2.1 (0.5-7.5)
1.6 (0.5-5.0)
0.6 (0.3-1.2)
Other adversity
0.5 (0.2-1.6)
0.4 (0.1-1.5)
0.4 (0.1-2.1)
Experience 2 or more ACE v. 0
1.9 (0.1-33.4)
3.7 (0.2-61.8)
10.0 (0.8-126.7)
Experience 3 or more ACE v. 0 3.4 (0.1-247.1) 3.5 (0.0-555.3) < 0.001 (< 0.001-0.011)

OR, odds ratio.

a. Based on discrete-time survival models with person-year as the unit of analysis pooled across the different DSM—IV disorders, controlling for age-at-interview, gender and person-year.

*P < 0.05, two-sided test.