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Role of LKB1 in nucleotide and adenosine-mediated activation of AMPK. HeLa cells were incubated with extracellular nucleotides, ATP, UTP and ADP (100 ìmol/L; 2 minutes) or adenosine (25 ìmol/L; 5 minutes). Representative Western blots show cell lysates immunoblotted with antibodies to P-AMPK (Thr-172) and AMPK-α. Representative Western blots of 3 independent experiments.
