Table 3.

Clusters of adjacent genes that show similar changes in expression when B. cenocepacia J2315 biofilms are exposed to H₂O₂ or NaOCl.

		Fold change in expression in treated biofilms vs untreated biofilms
Gene number	Annotation	H2O2 (30 min)	NaOCl (5 min)
BCAL1763	Putative exported protein	15.5	30.2
BCAL1764	Putative exported protein	5.3	15.3
BCAL1765	Putative exported protein	7.5	31.0
BCAL1766	OsmC-like protein (Ohr protein, see text)	18.0	75.2
BCAS0084	TetR family regulatory protein	5.9	3.8
BCAS0085	Organic hydroperoxide resistance protein	49.3	20.3
BCAS0086	Putative exported lipase	96.6	11.3
BCAM0930	Putative ankyrin-like protein (ankB)	2.7	NS
BCAM0931	Catalase precursor	5.7	NS
BCAM1216	Alkyl hydroperoxide reductase F subunit (ahpF)	15.5	2.1
BCAM1217	Alkyl hydroperoxide reductase C subunit (ahpC)	41.3	15.0
BCAL1688	Putative RNA polymerase σ 70 factor (orbS)	6.4	NS
IG1_1847123	IG between BCAL1688 and BCAL1689	2.9	NS
BCAL1689	Mbt-like protein (orbH)	3.8	NS
BCAL1690	Dioxygenase (orbG)	2.3	NS
BCAL2192	Conserved hypothetical protein (iscX)	2.4	NS
BCAL2193	Ferredoxin (fdx)	2.5	NS
BCAL2194	Chaperone protein HscA homologue (hscA)	2.4	NS
BCAL2195	Chaperone protein HscB homologue (hscB)	2.3	NS
BCAL2196	Iron-sulfur cluster assembly protein (iscA)	1.6	NS
BCAL2197	Iron-sulfur cluster scaffold protein (iscU)	3.4	NS
BCAL2198	Cysteine desulfurase (iscS)	2.9	NS
BCAL2199	Transcriptional regulator protein (iscR)	2.3	NS
BCAL1105	Exported protein	6.8	12.7
BCAL1106	Cytochrome b561 family protein	4.1	8.3
BCAL1107	Oxidoreductase	2.7	3.4
BCAL3477	Putative catalase	2.7	NS
BCAL3478	Putative RNA polymerase σ factor	3.4	NS

The results represent the fold change in gene expression in the treated biofilms compared to the gene expression in the untreated biofilms (based on the microarray analysis). NS: no significant change in expression was observed between the treated and the untreated biofilms (p > 0.05).