Table 3.

Mean Adjusted CDRS-R Total Scores for the 12-Week Analysis (N = 439)

	Fluoxetine alone		CBT alone		Combination (CBT + fluoxetine)		Pill placebo
	Youth with ADHD n = 14	Without ADHD n = 95	Youth with ADHD n = 14	Without ADHD n = 97	Youth with ADHD n = 15	Without ADHD n = 92	Youth with ADHD n = 19	Without ADHD n = 93
Baseline	56.08 ± 3.93	59.36 ± 4.24	60.01 ± 4.66	59.59 ± 4.78	58.59 ± 7.33	61.14 ± 4.78	55.55 ± 4.50	62.33 ± 4.43
Week 6	37.05 ± 6.03	40.37 ± 7.33	39.45 ± 5.68	44.98 ± 8.22	40.73 ± 8.54	37.58 ± 7.67	45.25 ± 5.30	44.59 ± 7.42
Week 12	33.29 ± 6.42	36.83 ± 8.11	35.95 ± 6.34	42.35 ± 8.96	37.08 ± 9.42	33.30 ± 8.14	43.31 ± 5.65	41.39 ± 8.07

Mean adjusted scores derived from the subgroup analyses.

Abbreviations: CDRS-R = Children's Depression Rating Scale–Revised; ADHD = attention-deficit/hyperactivity disorder; CBT = cognitive–behavioral therapy.