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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Int J Cancer. 2010 May 1;126(9):2112–2122. doi: 10.1002/ijc.24909

Figure 4.

Figure 4

Inhibition of dopamine synthesis decreases cholangiocarcinoma cell proliferation in vitro. Cholangiocarcinoma cells and the non-malignant cholangiocyte cell lines, H69 and HIBEC, were treated with various concentrations of α-methyl dopa (10-6 M to 10-8 M) for 48 hr. Cell proliferation was assessed using an MTS cell proliferation assay. Data are expressed as fold change in proliferation (average ± SEM, n=7) and the asterisk denotes p<0.05 compared to basal treatment within each cell line.