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. Author manuscript; available in PMC: 2011 Feb 26.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Jan 25;393(1):66–72. doi: 10.1016/j.bbrc.2010.01.080

Figure 2. Effect of CSE and H2O2 on SIRT1 phosphorylation in HUVECs.

Figure 2

HUVECs were treated with CSE (0.5% and 1.0%) and H2O2 (25, 50 and 100 μM) for indicated time points. A) CSE and H2O2 increased the phosphorylation of SIRT1 (at Ser27 and Ser47). B) and C) Histograms represent relative intensity of phosphorylated SIRT1 levels compared to respective control treatments (n=3). *P < 0.05, **P < 0.01, ***P < 0.001 vs. controls. p-SIRT1 (Ser27), phosphorylation of SIRT1 at Ser27; p- SIRT1 (Ser47), phosphorylation of SIRT1 at Ser 47.