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. Author manuscript; available in PMC: 2011 Mar 5.
Published in final edited form as: J Org Chem. 2010 Mar 5;75(5):1795–1798. doi: 10.1021/jo902697g

Table 3.

Enantioselective Carbonyl Crotylation of Furan Methanols via Iridium Catalyzed Transfer Hydrogenation.a

graphic file with name nihms177153u4.jpg
Entry Furan Methanol Product Isolated Yield (dr) ee (%)
1 R = H, 1a 4a 77%, 10:1 92 (R,R)
2 R = Me, 1b 4b 76%, 7:1 91 (R,R)
3 R =Ar, 1c 4c 95%, 10:1 95 (R,R)
a

As described for Table 1.