TABLE 1.
Reporter | Targeting Description |
---|---|
FL | Slow UPS degradation |
CL-1-FL | Targeted to E1–E3 by CL1-degron, rapid degradation |
4-Ub-FL | Ubiquitinated, targeted to 26S, rapid degradation |
p21-FL | Does not require ubiquitination, targeted to proteasome core by p21 |
Definition of abbreviation: UPS, ubiquitin-dependent proteasome system.