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. 2009 Jun 5;42(3):363–372. doi: 10.1165/rcmb.2008-0434OC

TABLE 1.

REPORTERS OF UBIQUITINATION-DEPENDENT DEGRADATION

Reporter Targeting Description
FL Slow UPS degradation
CL-1-FL Targeted to E1–E3 by CL1-degron, rapid degradation
4-Ub-FL Ubiquitinated, targeted to 26S, rapid degradation
p21-FL Does not require ubiquitination, targeted to proteasome core by p21

Definition of abbreviation: UPS, ubiquitin-dependent proteasome system.