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. Author manuscript; available in PMC: 2010 Mar 2.
Published in final edited form as: Crit Rev Oncol Hematol. 2006 May 23;59(2):85–97. doi: 10.1016/j.critrevonc.2006.02.002

Fig. 1.

Fig. 1

Schematic representation of the transcriptional repressors Gfi1 and Gfi1B. Both Gfi1 and Gfi1B bind to the consensus-DNA binding site 5′-AATCNNG-3′ with C2H2 type zinc-fingers on target genes. Once bound to DNA, Gfi1 and Gfi1B repress transcription through the N-terminal SNAG repressor domain.