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. Author manuscript; available in PMC: 2010 Mar 2.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2003 Jul 24;285(5):G822–G828. doi: 10.1152/ajpgi.00213.2003

Fig. 8.

Fig. 8

Inhibition of cAMP reduces chymotrypsinogen activation. Isolated acini were pretreated with the cAMP antagonist 8Br-Rp-cAMP (100 μM) or vehicle for 60 min before stimulation. After pretreatment, acini were treated as shown for 60 min and assayed for trypsin (A and C) and chymotrypsin activities (B and D). *P < 0.05 compared with paired treatment condition without 8Br-Rp-cAMP.