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Chymotrypsinogen activation reconstituted in ZG (A) and Mic (B) pancreatic fractions is dependent on Cyt and ATP. It is enhanced by the addition of Cyt and ATP and requires ATP hydrolysis (experimental conditions described in MATERIALS AND METHODS). Data are normalized to amylase content and expressed as fold vs. ZG/Mic + Cyt + ATP; n = 3. *P < 0.05 vs. no ATP condition; #P < 0.05 vs. ZG plus Cyt condition.
