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. Author manuscript; available in PMC: 2010 Mar 2.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2005 Dec 8;290(5):G894–G902. doi: 10.1152/ajpgi.00373.2005

Fig. 6.

Fig. 6

The protein kinase inhibitor H-89 does not affect trypsinogen activation (A and B) but decreases chymotrypsinogen activation (C and D) in ZG and Mic fractions. Assays were repeated as for Figs. 3 and 4 with the exception that some samples were preincubated with H-89 (1, 30, and 100 μM) for 30 min. Control experiments (i.e., in the absence of H-89) were preincubated with 1% DMSO, the vehicle for H-89. Data are normalized to amylase content and expressed as fold vs. ZG/Mic + Cyt + ATP; n = 3. Activation in Cyt alone was negligible (data not shown). *P < 0.05 vs. ZG/Mic + Cyt + ATP.