Table 2.

Hazard Ratio of Death or Cardiac Death by Post Randomization MI Status

	Number of Deaths†		HR of Death† (95% CI)	Nominal p-value for equality between HR	Number of Cardiac Deaths†		HR of Cardiac Death* (95% CI)	Nominal p-value for equality between HR
	Rev	IMT	Rev/IMT		Rev	IMT	Rev/IMT
All Patients(n = 2368)
MI	36	46	0.82 (0.53–1.27)	0.22	22	36	0.58* (0.34–0.99)	<0.001**
No MI	101	92	1.13 (0.86–1.50)		49	26	1.95* (1.21–3.14)
PCI Stratum(n = 1605)
MI	24	27	0.65 (0.37–1.13)	0.033*	13	20	0.44* (0.22–0.90)	<0.001**
No MI	67	53	1.33 (0.93–1.91)		31	13	2.49* (1.30–4.75)
CABG Stratum (n = 763)
MI	12	19	1.3 (0.63–2.71)	0.35	9	16	0.95 (0.41–2.17)	0.48
No MI	34	39	0.86 (0.55–1.37)		18	13	1.41 (0.69–2.87)
	IP	IS	IP/IS		IP	IS	IP/IS
All Patients (n = 2368)
MI	44	38	0.87 (0.57–1.35)	0.54	30	28	0.79 (0.47–1.32)	0.34
No MI	97	96	1.03 (0.77–1.36)		39	36	1.10 (0.70–1.73)

^†censored at last known MI follow-up

^*significant at nominal level

^**significant after Bonferroni adjustment for multiple tests done in the table

CABG = coronary artery bypass grafting; IP/IS = insulin provision/insulin sensitization; MI = myocardial infarction; PCI = percutaneous coronary intervention; Rev/Med = revascularization/medicine