Table 5.

Posterior 5th, 50th, and 95th percentiles for associative, disassociative, and mediated effects and for proportion of population in principal strata mediator classes: unconstrained under the stochastic monotonicity assumption and under the deterministic monotonicity assumption. Unadjusted and adjusted for age and race

	Unadjusted			Adjusted
	5th	50th	95th	5th	50th	95th
Unconstrained (MLE)
ae (-1.07,1.46)	− 0.094	0.076	0.237	− 0.044	0.035	0.114
de (-0.62,0.86)	− 0.074	0.054	0.179	− 0.030	0.034	0.098
me (-4.07,4.20)	− 1.857	0.159	2.28	− 2.32	0.018	2.31
Never mediators (0.271, 0.556)	0.329	0.416	0.502	0.353	0.402	0.451
Concordant mediators (0.159, 0.444)	0.211	0.298	0.384	0.258	0.308	0.356
Always mediators (0, 0.284)	0.062	0.145	0.229	0.106	0.148	0.192
Discordant mediators (0, 0.284)	0.057	0.139	0.225	0.098	0.141	0.185
Stochastic monotonicity (MLE)
ae (-1.07,1.46)	− 0.026	0.057	0.153	− 0.008	0.035	0.082
de (-0.62,0.86)	0.021	0.076	0.161	0.046	0.076	0.116
me (-4.07,4.20)	− 1.346	− 0.117	0.672	− 1.066	− 0.331	0.172
Never mediators (0.271, 0.556)	0.320	0.413	0.504	0.347	0.397	0.447
Concordant mediators (0.159, 0.444)	0.209	0.302	0.393	0.262	0.313	0.362
Always mediators (0, 0.284)	0.055	0.143	0.232	0.101	0.145	0.191
Discordant mediators (0, 0.284)	0.055	0.143	0.232	0.100	0.145	0.190
Monotonicity (MLE)
ae (0,1)	0.010	0.125	0.330	0.055	0.117	0.201
de (0,0.069)	0.019	0.056	0.093	0.034	0.054	0.077
me (-0.190,1)	− 0.161	0.159	0.690	− 0.024	0.175	0.406
Never mediators (0.556)	0.531	0.555	0.579	0.513	0.538	0.562
Concordant mediators (0.160)	0.132	0.161	0.189	0.151	0.179	0.209
Always mediators (0.284)	0.269	0.284	0.300	0.266	0.283	0.299