Table 1.
Characteristics of post-mortem brain tissue from patients with schizophrenia and normal comparison subjects
| Characteristic | Tissue from patients with schizophrenia (n = 10) | Tissue from normal comparison subjects (n = 9) | ||
|---|---|---|---|---|
| Mean | SD | Mean | SD | |
| Subject’s gender (N) | ||||
| Male | 4 | 3 | ||
| Female | 6 | 6 | ||
| Neuregulin-1 genotype (N) | ||||
| TT | 4 | 4 | ||
| CT/CC | 6 | 4 (1 not determined) | ||
| Age at death (years) | 63.70 | 12.21 | 64.56 | 14.51 |
| Post-mortem interval (h) | 17.10 | 8.77 | 27.33 | 26.74 |
| pH | 6.55 | 0.33 | 6.63 | 0.37 |
| Storage time interval (months) | 27.82 | 10.76 | 24.59 | 8.29 |
| Age at onset (years) | 24.60 | 7.36 | ||
| Duration of the disease (years) | 39.10 | 11.77 | ||
| Duration of hospitalization (years) | 25.10 | 15.32 | ||
| Duration of antipsychotic medication (years) | 35.00 | 9.72 | ||
| Last dose of antipsychotic medication in chlorpromazine equivalents (CPE in gram) | 436.90 | 452.10 | ||
| Cumulative dose (last ten years) of antipsychotic medication in chlorpromazine equivalents (CPE in kilogram) | 3.59 | 3.04 | ||