Table 2. Demographic and PD Features: PD patients with and without a Lifetime Anxiety Disorder.
| Demographic Features | Total sample (n=127) | Non-Anxious (n=64) | Anxiety Disorder (n=63) | p-value |
|---|---|---|---|---|
| Current Age (years) | 67.0 (11.0) | 68.8 (11.3) | 65.1 (10.6) | .057 |
| Gender (male/female) | 83/44 | 43/21 | 40/23 | .662 |
| MMSE | 28.1 (1.8) | 28 (2.0) | 28.2 (1.6) | 0.726 |
| Lifetime History Depressive Disorder, % (n) | 65% (82) | 55% (35) | 75% (47) | 0.019 |
| Antidepressant Therapy, % (n) | 47% (60) | 38% (24) | 57% (36) | 0.027 |
| Family Psychiatric History, % (n) | 42% (53) | 31% (20) | 54% (33) | 0.010 |
| Quality of Life (PDQ-8) | 6.2 (4.7) | 5.3 (4.5) | 7.1 (4.7) | 0.025 |
| PD Features | ||||
| Age Symptom onset (years) | 59.0 (13.1) | 61.0 (13.7) | 57.0 (12.1) | 0.088 |
| Symptom Duration (years) | 7.9 (5.5) | 7.8 (5.9) | 8.0 (5.1) | 0.812 |
| I-18, I ½-2 | I-6, I ½-1 | I-12, I ½-1 | ||
| Hoehn and Yahr Stage | II-64, II ½-23 | II-31, II ½-14 | II-33, II ½-9 | 0.447 |
| III-14, IV-5, V-1 | III-9, IV-2, V-1 | III-5, IV-3, V-0 | ||
| UPDRS Motor Subscore | 18.0 (10.2) | 18.5 (10.9) | 17.4 (9.4) | 0.558 |
| Total L-DOPA Equivalents | 646 (412) | 639 (356) | 656 (463) | 0.813 |
| Agonist Use, %(n) | 31% (39) | 39% (25) | 22% (14) | 0.039 |
| Presence of Motor Fluctuations | 45.7% (58) | 39.0% (25) | 52.4% (33) | 0.132 |
Mean (SD); UPDRS, Unified Parkinson's Disease Rating Scale