Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Dec 24;29(3):655–665. doi: 10.1038/emboj.2009.383

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2010, European Molecular Biology Organization

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation without specific permission.

PMC Copyright notice

Components of the clathrin uncoating process. (A) Domain organization of Hsc70 (top), auxilin (middle) and clathrin heavy chain (bottom). Residue numbers for domain or regional boundaries are shown below the bars. (B) A clathrin triskelion (left) and its packing within the lattice of a coat (right). The various regions of the heavy chain are labelled; the ordered, 71-residue α-helical segment of the light chain is also shown. Three symmetry-distinct vertices are colour-coded, yellow, blue (the hub of the blue triskelion) and green. (C) Side view of the triskelion (left), illustrating the pucker at the apex, and a close-up of the hub region, including the helical tripod and the QLMLT sequence near the C-terminus.