Figure 4.
Enhanced CD36 and MCP-1 expression in the hyperlipidemic periphery. A, CD36 mRNA in normal and hyperlipidemic macrophages. B, Western blot analysis for CD36 protein in normal and hyperlipidemic macrophages. C, MCP-1 gene expression in normal and hyperlipidemic macrophages. D, Plasma MCP-1 level (picograms per milliliter). H, Heart (CD36-positive control); −/−, macrophages from CD36 KO mice (CD36 negative control); 0 h, nonischemic control; 6 or 72 h, postischemic time point; ND/WT, normolipidemic mice; HD/KO, hyperlipidemic mice. n = 4–5 per group. *p < 0.05 and **p < 0.01 versus ND/WT.