Figure 5.

Foam cell formation in the hyperlipidemic brain. A–D, Oil Red-O staining in the ipsilateral (A–C) and contralateral (D) side of a hyperlipidemic brain 3 d after ischemia. No foam cells were observed in the normolipidemic brain, and Oil Red-O staining in the ipsilateral side of the normolipidemic brain was similar to D. The asterisks in A (40×) and B (100×) indicate the same region. The outline in B indicates the area of photomicrograph C (200×). E, Photomicrograph of CD36 immunohistochemistry performed in the adjacent section of C. F, Photomicrograph of CD36 immunohistochemistry (200×) performed in the adjacent section of D.